Thesis of Vesber | Foldable Capsular Vitreous Body (FCVB): Saving Patients From the Pain of Eyeball Removal.

Thesis

1. Gao Q#*, Mou S, Ge J, To CH, Hui Y, Liu A, Wang Z, Long C, Tan J.A new strategy to replace the natural vitreous by a novel capsule-like artificial vitreous body with pressure-control valve. Eye (Lond). 2008;22(3):461-8.

2. Gao Q#*, Chen X, Ge J, Liu Y, Jiang Z, Lin Z, Liu Y. Refractive shifts in four selected artificial vitreous substitutes based on Gullstrand-Emsley and Liou-Brennan schematic eyes. Invest Ophthalmol Vis Sci. 2009;50(7):3529-34.

3.Liu Y, Jiang Z, Gao Q*, Ge J, Chen J, Cao X, Shen Q, Ma P. Technical Standards of a Foldable Capsular Vitreous Body in Terms of Mechanical, Optical, and Biocompatible Properties. Artif Organs. 2010;34(10):836-45.

4.Liu Y, Ke Q, Chen J, Wang Z, Xie Z, Jiang Z, Gao Q*. Sustained mechanical release of dexamethasone sodium phosphate sustained mechanical release in the foldable capsular vitreous body. Invest Ophthalmol Vis Sci. 2010;51(3):1636-42. Invest Ophthalmol Vis Sci. 2010;51(3):1636-42.

5.Chen X, Liu Y, Jiang Z, Zhou L, Ge J, Gao Q*. Protein kinase Cα downregulation via siRNA-PKCα released from foldable capsular vitreous body in cultured human retinal pigment epithelium cells. Int J Nanomedicine. 2011;6:1303-11.

6.Chen J, Gao Q*,Liu Y, Ge J, Cao X, Luo Y, Huang D, Zhou G, Lin X. Clinical device-related article evaluation of morphology and functions of a foldable capsular vitreous body in the rabbit eye. J Biomed Mater Res B Appl Biomater. 2011;97(2):396-404.

7.Zhang R, Wang T, Xie C, Lin X, Jiang Z, Wang Z, Liu Y, Luo Y, Long C, He L, Wang P, Gao Q*. Evaluation of supporting role of a foldable capsular vitreous body with magnetic resonance imaging in the treatment of severe retinal detachment in human eyes. Eye (Lond). 2011;25(6):794-802.

8.Lin X, Ge J, Gao Q*, Wang Z, Long C, He L, Liu Y, Jiang Z. Evaluation of the flexibility, efficacy, and safety of a foldable capsular vitreous body in the treatment of severe retinal detachment. Invest Ophthalmol Vis Sci. 2011;52(1):374-81.

9.Lin X, Wang Z, Jiang Z, Long C, Liu Y, Wang P, Jin C, Yi C, Gao Q*. Preliminary efficacy and safety of a silicone oil-filled foldable capsular vitreous body in the treatment of severe retinal detachment. Retina, 2012;32(4):729-41.

10.Jiang Z, Wang T, Pan B, Xie Z, Wang P, Liu Y, Gao Q*. Evaluation of the levofloxacin release characters from a rabbit foldable capsular vitreous body. Int J Nanomed. 2012;7:1-10.

11.Wang P, Gao Q*, Lin X, Zhang S, Hu J, Liu Y, Xu N, Ge J. Comprehensive analysis of inflammatory immune mediators of the intraocular fluid aspirated from the foldable capsular vitreous body filled-eyes. PLoS One.2012;7(10):e46384.

12.Jiang Z, Wang P, Pan B, Xie Z, Li D, Wang T, Liu Y, Yuan Z, Gao Q*. Evaluation of Levofloxacin Release Characteristics from a Human Foldable Capsular Vitreous Body In Vitro. J Ocul Pharmacol Ther. 2012;28(1):33-40.

13.Wang P, Gao Q*, Jiang Z, Lin J, Liu Y, Chen J, Zhou L, Li H, Yang Q, Wang T. Biocompatibility and retinal support of a foldable capsular vitreous body injected with saline or silicone oil implanted in rabbit eyes. Clin Experiment Ophthalmol. 2012;40(1): e67-75.

14.Feng S, Chen H, Liu Y, Huang Z, Sun X, Zhou L, Lu X, Gao Q*. A Novel Vitreous Substitute of Using a Foldable Capsular Vitreous Body Injected with Polyvinylalcohol Hydrogel. Sci Rep. 2013;3:1838.

15.Chen H, Feng S, Liu Y, Huang Z, Sun X, Zhou L, Lu X*, Gao Q*. Functional evaluation of a novel vitreous substitute using polyethylene glycol sols injected into a foldable capsular vitreous body. J Biomed Mater Res A. 2013;101(9):2538-47.

16.Wang T, Huang X, Gao Q*, Feng L, Xie Z, Jiang Z, Liu Y, Li Y, Lin X, Lin J. A Preliminary Study to Treat Severe Endophthalmitis via a Foldable Capsular Vitreous Body with Sustained Levofloxacin Release in Rabbits. Invest Ophthalmol Vis Sci. 2013;54(1):804-12.

17.Yang W, Yuan Y, Zong Y, Huang Z, Mai S, Li Y, Qian Y, Liu Y& Gao Q*. Preliminary Study on Retinal Vascular and Oxygen-related Changes after Long-term Silicone Oil and Foldable Capsular Vitreous Body Tamponade.2014;5272.

18.Mai S,Lin L,Yang W,Deng X, Xie Z,Zong Y, Li Y,and Gao Q*.In Vitro and In Vivo Release Characteristics of Tacrolimus (FK506) from an Episcleral Drug-Delivery Implant.2014;10.1089.

19.Huang Z, Yang W, Zong Y, Qiu S, Chen X, Sun X, Zhou Y, Xie Z, Gao Q*.A study of the dexamethasone sodium phosphate release properties from a periocular capsular drug delivery system. Drug Deliv. 2016;23(3):849-57.

20.Gao Q*, Fu Y, Hui YN. Vitreous substitutes: challenges and directions. Int J Ophthalmol. 2015;8(3):437-40.

21.Lin X, Sun X, Wang Z, Jiang Z, Liu Y, Wang P, Gao Q*. Three-Year Efficacy and Safety of a Silicone Oil-Filled Foldable-Capsular-Vitreous-Body in Three Cases of Severe Retinal Detachment. Transl Vis Sci Technol. 2016;5(1):2.

22.Feng X, Li C, Zheng Q, Qian XG, Shao W, Li Y, Li W, Yin L, Wang Y, Gao Q*. RISK OF SILICONE OIL AS VITREOUS TAMPONADE IN PARS PLANA VITRECTOMY: A Systematic Review and Meta-Analysis. Retina. 2017 Nov;37(11):1989-2000.

23. Xiangyang Zhang, Xuemin Tian,Lisa Guo, Xiaodan Li & Yong Jia. Study on the effectiveness and safety of Foldable Capsular Vitreous Body implantation.BMC Ophthalmology volume 19, Article number: 260 (2019)

24.Clinical Observation and perception of foldable capsular vitreous body implantation in 73 case

25.Liang Zhang, Jingwen Liu, Shenwen Liu,Bo Qin. Implantation of Foldable Capsular Vitreous Body for the Treatment of Acute Retinal Necrosis Syndrome: A Case Report.Ophthalmic Surg Lasers Imaging Retina;2020; 10.3928/23258160-20201104-09

26. Preliminary clinical application of foldable capsular vitreous body in severe silicone oil-dependent eyes.Annals of Palliative Medicine. 2021 10.21037/apm-21-2554

27. Reattachment After Foldable Capsular Vitreous Body Implantation in Severe Retinal Detachment Eyes.Transl Vis Sci Technol. 2021, 10.1167/tvst.10.11.8

28.Zhongyu Zhang. Shujie Liu. Fang Xie. Bo Jiang. Meng Sun.Dawei Sun. Comparison of Viscoelastic Substance Injection Versus Air Filling in the Anterior Chamber During Foldable Capsular Vitreous Body (FCVB) Implant Surgery: A Prospective Randomized Controlled Trial. Advances in Therapy. 2021, 10.1007/s12325-021-01840-5. Epub 2021 Aug 5.

29.Jin Deng, Hu-Ping Song, Rong-Le Zhou, Tao Chen, Jian-Zhou Wang, Zhao-Liang Zhu. Evaluation of the long-term effect of foldable capsular vitreous bodies in severe ocular rupture. Int J Ophthalmol. 10.18240/ijo.2021.12.19

30.Xiangzhong Xu, Huimin Ge, Jiajun Li, Weihong Shang, Yuke Ji, Weihua Yang , and Keran Li. Outcomes of a Foldable Capsular Vitreous Body Implantation: A Retrospective Study. Dis Markers. org/10.1155/2021/6575195

31.Baihui Zeng, Qian Wang, Guiqin Sui, Mingxuan Wang, Wei Xie, Jinling Fu. Foldable capsular vitreous body implantation for treatment of traumatic retinal detachment: two case reports. J Int Med Res.2021.10.1177/0300060521990257

32.CHUN ZHANG, RUIHAN XIAO, ANAN WANG, ZHENQUAN ZHAO. CAPSULAR VITREOUS BODY VERSUS SILICONE OIL ENDOTAMPONADE FOR TREATMENT OF NO LIGHT PERCEPTION AFTER SEVERE OCULAR TRAUMA. RETINA ,2022.10.1097/IAE.0000000000003336

33.Meili Li, YuTang, Suyan Li, Zhengpei Zhang, Lina Guan, Jie Li, Jing Xu,Sujuan Ji. Foldable Capsular Vitreous Body Implantation for Complicated Retinal Detachment Caused by Severe Ocular Trauma. RETINA ,2022.10.1097/IAE.0000000000003493